Bloomberg
Merck's diabetes drug Januvia succeeds in heart safety trial
Reuters
(Reuters) – Merck and Co's diabetes drug Januvia achieved the main goal of a long-awaited heart safety study, according to preliminary results released by the drugmaker on Monday, likely removing a cloud of uncertainty from its biggest product.
Merck Gains as Januvia Diabetes Drug Doesn't Add to Heart RiskBloomberg

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Science Daily
Diabetes drug found in freshwater is a potential cause of intersex fish
Science Daily
A study by Rebecca Klaper at the University of Wisconsin-Milwaukee determined exposure to the diabetes medicine metformin causes physical changes in male fish exposed to doses similar to the amount in wastewater effluent. In addition to intersex …
Diabetes drug metformin linked with intersex freshwater fishUPI.com
Diabetes drug metformin found in freshwater is potential cause of intersex fishScience Codex
Male fish producing eggs due to diabetes drug traces in freshwaterInternational Business Times UK
Zee News
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MedPage Today
Investigational Diabetes Drug Eyed for Steatohepatitis
MedPage Today
Note that this randomized trial of a novel type-2 diabetes agent showed promise in reducing alanine aminotransferase levels, suggesting it may have a role in NASH. Be aware that the beneficial effect on liver enzymes may have been due to weight loss.

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Bloomberg
AstraZeneca's diabetes drug Onglyza may increase death rate -FDA
AOL News
In December 2008, the FDA issued guidance requiring drug companies to conduct studies to show that new diabetes drugs do not increase cardiovascular risk. The guidance was developed amid growing concern about the safety of many diabetes drugs.
AstraZeneca's Diabetes Drug May Raise Death Risk, FDA SaysBloomberg
AstraZeneca diabetes drug may increase risk of heart failure and deathModernHealthcare.com

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Bloomberg
FDA pulls diabetes drug citing increased risk of death – AOL.com
AOL News
The Food and Drug Administration is pulling a Type 2 diabetes drug produced by AstraZeneca off the market after a new study shows it increases overall death rates in patients. According to their study, patients who took Onglyza were at a greater risk
AstraZeneca's diabetes drug Onglyza may increase death rate -FDAReuters
AstraZeneca's Diabetes Drug May Raise Death Risk, FDA SaysBloomberg
AstraZeneca diabetes drug may increase risk of heart failure and deathModernHealthcare.com

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Should FDA Penalize Drug Makers Over Diabetes Drug Ads?
Wall Street Journal (blog)
A consumer watchdog has asked the FDA to stop several drug makers from promoting their diabetes medicines for losing weight, because the drugs were not approved for this purpose. In a letter to the FDA, Public Citizen says the ads are ubiquitous – they …
Off-label promotions of diabetes meds sometimes nonsensical, watchdog warns McKnight’s Long Term Care News
FDA Must Block Off-Label Diabetes Drug Promos, Group SaysLaw360 (subscription)

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Gestational Diabetes Drug Might Raise Babies' Complication Risk – WebMD
WebMD
Although the initial trial data suggested it was safe, large studies including this one have raised concerns about the safety of its use," said Dr. Richard Holt, author of an accompanying editorial in the journal, and a professor of diabetes and
Risk for adverse neonatal outcomes linked to glyburideHealio
Glyburide associated with more risk of adverse events than insulin in newbornsMedical Xpress
Glyburide Use in Moms May Up Neonatal Adverse EventsMonthly Prescribing Reference

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Yale News
Banned weight-loss drug could combat liver disease, diabetes
Science Now
A drug the U.S. government once branded “extremely dangerous and not fit for human consumption” deserves a second chance, a study of rats suggests. Researchers report that a slow-release version of the compound reverses diabetes and nonalcoholic …
Yale researchers reverse type 2 diabetes and fatty liver disease in ratsYale News
First World War explosive could reverse diabetes, says Yale UniversityTelegraph.co.uk
Watered-down version of First World War explosive reverses diabetes in miceZee News
International Business Times AU
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Bidness ETC
FDA approves Sanofi's diabetes drug Toujeo
Reuters
(Reuters) – U.S. health regulators on Wednesday approved Sanofi's diabetes drug Toujeo, a more potent follow-up to the French drugmaker's top-selling insulin product Lantus. The Food and Drug Administration approved the once daily, long-acting basal …
FDA OKs Sanofi's Toujeo. Will a diabetes drug price war follow?FierceBiotech
FDA Approves a New Sanofi Diabetes Drug, But How Much Will it Matter?Wall Street Journal (blog)
Sanofi diabetes drug awaits imminent EU green lightBusiness Insider
Bidness ETC -WTAQ
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UPDATE 4-Isis Pharma's diabetes drug takes longer than expected to work
Reuters
Feb 3 (Reuters) – Isis Pharmaceuticals Inc's experimental diabetes drug took longer than expected to show a statistically significant reduction in blood sugar levels in patients with Type 2 diabetes already on standard treatment. Large drugmakers Novo …
Isis Pharma Time Shifts Diabetes Drug Trial to Embellish ResultsTheStreet.com
Isis Pharma's diabetes drug takes longer than expected to workYahoo News
Isis hails a Phase II diabetes victory, with caveatsFierceBiotech

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